Thomas Hutter is a young man full of hope. Ellen, his wife, wish him a nice trip since he must travel to Transylvania to sell a property to Count Orlok, the vampire Nosferatu!

This buys a house that is opposite that of Hutter. During the transaction, Nosferatu seen a picture of the beautiful Ellen. It makes it to its new ownership, but the arrival of vampire brings with it the plague and death for the citizens of this small community of Wisbourg, Germany.

Fortunately, Ellen understands the true nature of his neighbour and sacrifices herself by offering her vampire blood to save the lives of others.